16 genes to know in advance which infected individuals will develop TB disease

Q.  A set of how many genes can be used to know in advance which infected individuals will develop TB disease?
- Published on 28 Mar 16

a. 10
b. 12
c. 8
d. 16

ANSWER: 16
 
  • Now, a set of 16 genes can be used as biomarkers to know in advance which infected individuals will develop TB disease.
  • The genes become more active in those who will develop TB disease in the next one or two years than in people who will continue to stay healthy.
  • Since the infected population acts as a huge reservoir and as all infected people across the world cannot be given preventive TB treatment for at least six months, picking out only those who are very likely to develop the disease and providing them preventive treatment will go a long way in reducing the TB burden in the world.
  • The ability of the blood-based signatures to predict progression to active tuberculosis disease in healthy individuals can pave the way for the establishment of diagnostic methods that are scalable and inexpensive.

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