Disadvantages of Inactivated Polio Vaccine (IPV)
Q. Which of the following are disadvantages of Inactivated Polio Vaccine (IPV)?
1) It induces very low levels of immunity in the intestine
2) It is costlier than oral vaccine
3) Administration requires trained health workers- Published on 02 Aug 16a. 1, 3
b. 1, 2
c. 2, 3
d. All of the above
ANSWER: All of the above
- Advantages –
1. As IPV is not a 'live' vaccine, it carries no risk of vaccine-associated polio paralysis.
2. IPV triggers an excellent protective immune response in most people.- Disadvantages –
1. IPV induces very low levels of immunity in the intestine. As a result, when a person immunized with IPV is infected with wild poliovirus, the virus can still multiply inside the intestines and be shed in the faeces, risking continued circulation.
2. IPV is over five times more expensive than oral polio vaccine.
3. Administering the vaccine requires trained health workers and sterile injection equipment and procedures.- Safety - IPV is one of the safest vaccines in use. No serious systemic adverse reactions have been shown to follow vaccination.
- Efficacy - IPV is highly effective in preventing paralytic disease caused by all three types of poliovirus.
