Elevated methylation signature which is biomarker of 5 different types of cancer found
Q. Scientists have found an elevated methylation signature around a gene called _______ unique to tumors.- Published on 08 Feb 16a. ZNS154
b. ZNF154
c. ANS154
d. XNS154
ANSWER: ZNF154
A tell tale marker of 5 different types of cancer was discovered by NIH researchers from the US, increasing chances of diagnosing cancer with a simple blood test. Scientists also found evidence that a methylation signature like this may be present in many more types of cancer. This specific signature occurs as DNA from cancer undergoes chemical modification through a process known as methylation. This controls the functioning of specific genes such as a dimmer on a light switch. Greater amounts of DNA methylation are present in some DNA tumors, decreasing the activity of the gene. Elevated methylation signature around the gene known as ZNF154 unique to tumors was found by the scientists.