Fountain of youth gene discovered
Q. Which gene thought to be inactive in adults plays a vital role in preventing heart attacks and stroke and could also delay ageing?- Published on 25 May 16a. Fountain of youth gene
b. Oct4
c. Oct5
d. Both a and b
e. None of the above
ANSWER: Both a and b
A gene, thought to be inactive in adults, may actually play a vital role in preventing heart attacks and stroke . and could also delay some of the effects of ageing, scientists have found.
- The gene, Oct4 , plays a key role in the development of all living organisms, but scientists have, until now, thought it was permanently inactivated after embryonic development.
- Researchers have determined the gene plays a critical protective role during the formation of atherosclerotic plaques inside blood vessels.
- The rupturing of these plaques is the underlying cause of many heart attacks and strokes.
- The researchers found that Oct4 controls the movement of smooth muscle cells into protective fibrous "caps" inside the plaques — caps that make the plaques less likely to rupture.
- They also have provided evidence that the gene promotes many changes in gene expression that are beneficial in stabilising the plaques.