Haemophilia is a genetic blood disorder.
Q. Which of the following is/are true regarding Haemophilia?
1) Haemophilia is a disorder of bone and bone marrow
2) It is a genetic disease.- Published on 08 Feb 16a. Only 1
b. Only 2
c. Both 1 and 2
d. Neither 1 nor 2
ANSWER: Only 2
- Haemophilia (also spelled hemophilia) is a group of disorders that impairs the body's ability to control blood clotting, which is used to stop bleeding when a blood vessel is broken.
- Haemophilia is a genetic disorder in which the patient tends to bleed excessively. Anti-haemophilic factor concentrates (VIII & IX) that are given to patients to control the bleeding.
- These concentrates are proteins that help the blood clot. Indian patients depend on American pharmaceutical company Baxter International for the proteins.
- Haemophilia A (clotting factor VIII deficiency) is the most common form of the disorder, present in about 1 in 5,000–10,000 male births. Haemophilia B (factor IX deficiency) occurs in around 1 in about 20,000–34,000 male births.
- Like other recessive sex-linked, X chromosome disorders, haemophilia is more likely to occur in males than females. This is because females have two X chromosomes while males have only one, so the defective gene is guaranteed to manifest in any male who carries it.
