Researchers discover mutation in gene MSH3 which can lead to hereditary colon cancer

Q.  Researchers have discovered that a mutation in gene ___ can lead to a form of hereditary colon cancer.
- Published on 01 Aug 16

a. MSH3
b. MSH4
c. MSH5
d. MSH6

ANSWER: MSH3
 
Scientists have discovered a mutation in a gene leading to a hereditary form of colon cancer not identified earlier.
  • Researchers have discovered genetic changes in the MSH3 gene in patients and identified a new form of colon cancer.
  • Formation of large number of polyps in the colon has high chances of being developed into colon cancer, if left untreated.
  • Colon polyps form mushroom shaped growths from the mucosa and are several millimetres to centimetres in size.
  • Though generally benign, they can turn into malignant tumours or colon cancer through polyposis.

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