Scientists discover molecule targeting drug to promote easier organ transplants, develop laser from bacteria
Q. Chinese scientists have discovered a drug that can regenerate the tissue and could make organ transplant more easier in the future. What is it called?- Published on 22 Aug 16a. XMY-MP-1
b. XMU-MP-1
c. XMJ-MP-1
d. None of the above
ANSWER: XMU-MP-1
Chinese scientists have discovered a small molecule that can regenerate the tissue and could make organ transplant much easier in the future.
- Research was led by professors in Xiamen and Peking University.
- The scientists have discovered a drug called XMU-MP-1 which can repair and regenerate the liver, skin and intestines.
- Pills may do away for the need for operations for organ transplant or complex biomaterial and cell therapies.
- A critical signalling molecule in the Hippo pathway which controls organ size is impacted by the drug.
- XMU-MP-1 inhibits the activity of MST1/2 the central component of this pathway and promotes cell growth in four different mouse models of acute and chronic injuries.
- This includes acetaminophen induced injury, a common cause of liver failure worldwide.
- The Chinese have applied for the patent and are cooperating with pharma companies to produce the medicine.
- Scientists have also developed laser from florescent jellyfish protein grown in bacteria.
- These lasers have the potential to be fa more efficient and compact than conventional ones and could open up the research venues in quantum physics and optical computing according to researchers.
- Breakthrough represents a major advance in polariton lasers.
- By repurposing the fluorescent proteins revolutionising biomedical imaging and allowing scientists to monitor processes inside cells, team has created a pollution laser operating at room temperature powered by nanosecond pulses measuring a billionth of a second.
- Picosecond pulses of suitable energy are 1000 times more difficult to make than nanosecond pulses so it simplifies making these pollution lasers quite significantly.
- Scientists from University of Wurzburg and Dresden University of Technology in Germany genetically engineered e-coli bacterial to produce enhanced green fluorescent protein (eGFP).
- Researchers filled optical micro cavities with this protein before subjecting them to optical pumping where nanosecond flashes of light are being used to bring the system up to the required energy to create laser light.
- Once the threshold for polariton lasing has been reached, pumping resulted in conventional lasing.
- This confirmed the first emission was due to polariton lasing
