Single neuron carries more than 1000 genetic mutations
Q. According to scientists, a single nerve cell in the brain carries how many genetic mutations?- Published on 06 Oct 15a. More than 1000
b. Less than 1000
c. 1000
d. None of the above
ANSWER: More than 1000
A single neuron/nerve cell in a normal adult brain may have more than 1000 genetic mutations, many of which could be harmless, according to new research by Maryland-based Howard Hughes Medical Institute (HHMI) scientists. The mutations manifest after the brain becomes fully developed. For the study, the scientists isolated and sequenced the genomes of 36 neurons from healthy brains donated by three adults after their deaths and sequenced DNA that they isolated from cells in each individual's heart. They found each never cell’s genome was unique with more than 1000 point mutations that change a single letter of the genetic code. These mutations have a unique signature of their own and occur when cells are expressing the genes.
