Young adults with increased Alzheimer’s risk show altered brain activity in entorhinal cortex

Q.  Which part of the cortex has been implicated in Alzheimer’s disease on 26th October 2015 by scientists?
- Published on 27 Oct 15

a. Cerebral cortex
b. Temporal Lobe
c. Frontal Lobe
d. Entorhinal cortex

ANSWER: Entorhinal cortex
 
Young adults with increased risk of Alzheimer’s from a genetic perspective have activation patterns in brain region critical for spatial navigation. The grid cell system in the entorhinal cortex was exampled by German researchers. In this cortex, grid cells fire in spatial grid pattern. Risk carriers have a less stable grid pattern in the entorhinal cortex decades before they develop this dementia. They also moved less frequently in centre of virtual landscape which suggests altered navigation strategy.

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